Portugal forward Diogo Jota will miss the 2022 World Cup finals in Qatar after he sustained a calf injury in Liverpool's 1-0 win over Manchester City in October.
Speaking two days after Jota was carried off the pitch at Anfield on a stretcher, Liverpool manager said the prognosis was ‘not good news’.
“Yes he will miss the World Cup,” said Klopp. “Pretty serious injury of the calf muscle. Sad news for the boy, us and Portugal.”
Portugal, who will be appearing in their sixth successive World Cup, will also be without Wolves winger Pedro Neto who requires surgery for an ankle injury sustained in a Premier League game against West Ham.
In the qualifiers, Portugal finished second in Group A so they had to go through the play-off path. A Bruno Fernandes brace allowed them to see off North Macedonia and book their place at Qatar.
Head coach Fernando Santos has been in charge since 2014. In the 2016 Euros he guided Portugal to glory after they defeated hosts France to lift the trophy for the first time. In the last edition of the World Cup and Euros, their tournament ended at the last-16 stage.
Their final World Cup warm-up preparations brought mixed results, beating the Czech Republic 4-0 before then losing 1-0 to Spain in the last Nations League game.
Portugal World Cup 2022 squad
Portugal announced their 26-man squad on November 10, which features a raft of Premier League players; City, United and Wolves are represented in triplicate, plus lone Fulham player, Joao Palhinha.
Goalkeepers: Diogo Costa (FC Porto), Jose Sa (Wolverhampton Wanderers FC), Rui Patricio (AS Roma)
Defenders: Diogo Dalot (Manchester United), Joao Cancelo (Manchester City), Danilo Pereira (PSG), Pepe (FC Porto), Ruben Dias (Manchester City), Antonio Silva (SL Benfica), Nuno Mendes (PSG), Raphael Guerreiro (Borussia Dortmund)
Midfielders: Joao Palhinha (Fulham FC), Ruben Neves (Wolverhampton Wanderers FC), Bernardo Silva (Manchester City), Bruno Fernandes (Manchester United), Joao Mario (SL Benfica), Matheus Nunes (Wolverhampton Wanderers FC), Otavio Monteiro (FC Porto), Vitinha (PSG), William Carvalho (Real Betis)
Forwards: Andre Silva (RB Leipzig), Cristiano Ronaldo (Manchester United), Goncalo Ramos (SL Benfica), Joao Felix (Atletico Madrid), Rafael Leao (AC Milan), Ricardo Horta (SC Braga).
Who are likely to be the star names in the squad?
Cristiano Ronaldo will almost certainly be taking part in his last World Cup. The all-time leading international goalscorer will look to add the World Cup to his horde of trophies.
Bruno Fernandes will also be one to watch, as will Rafael Leao, who has been impressing at AC Milan this season.
What are Portugal’s fixtures?
What is Portugal’s World Cup record?
Portugal have appeared at the tournament seven times. On their debut appearance in 1966 they recorded their highest ever finish: third place.
Portugal have appeared at the previous five editions of the World Cup and fell in the round of 16 at Russia 2018 when they were beaten 2-1 by Uruguay.
Argentina | Australia | Belgium | Brazil | Cameroon | Canada | Costa Rica | Croatia | Denmark | Ecuador | England | France | Germany | Ghana | Iran | Japan | Mexico | Morocco | Netherlands | Poland | Portugal | Qatar | Saudi Arabia | Senegal | Serbia | South Korea | Spain | Switzerland | Tunisia | Uruguay | USA | Wales
Portugal are currently a best price of 14/1 to win World Cup 2022.
Other leading contenders...
Information correct as of November 13