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New Orleans Saints at Carolina Panthers: Predictions, picks and odds for NFL Week 2 game

The New Orleans Saints (1-0) travel north to take on the Carolina Panthers (0-1), the only NFC South team that lost in Week 1.

Both teams feature new quarterbacks.

Rookie Bryce Young struggled in his NFL debut and threw two interceptions as Carolina lost to the Atlanta Falcons. He will be making his home debut at Bank of America Stadium in a primetime game on Monday.

Derek Carr led the Saints to a victory in his first start in Black and Gold. Chris Olave and Rashid Shaheed stepped up in Alvin Kamara's absence. The star running back will sit out again this week as he serves a suspension for a Las Vegas fight.

The Panthers won both division matchups last year with a much different team.

Will New Orleans' veteran leadership outduel the hungry rookie this season?

SETTLE IN: Bryce Young's rough NFL debut for Panthers is no reason to panic about the No. 1 pick

Panthers vs. Saints odds, moneyline, over/under

The New Orleans Saints are favorites to defeat the Carolina Panthers, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.

  • Spread: Saints (-3)

  • Moneyline: Saints (-165); Panthers (+140)

  • Over/under: 39.5

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Carolina Panthers safety Sam Franklin Jr. waits for a punt against New Orleans Saints cornerback Alontae Taylor and safety J.T. Gray during a January 2023 matchup.
Carolina Panthers safety Sam Franklin Jr. waits for a punt against New Orleans Saints cornerback Alontae Taylor and safety J.T. Gray during a January 2023 matchup.

NFL Week 2 odds, predictions and picks

Vikings vs. Eagles | Packers vs. Falcons | Raiders vs. Bills | Ravens vs. Bengals | Seahawks vs. Lions | Colts vs. Texans | Chiefs vs. Jaguars | Bears vs. Buccaneers | Chargers vs. Titans | Giants vs. Cardinals | 49ers vs. Rams | Jets vs. Cowboys | Commanders vs. Broncos | Dolphins vs. Patriots | Saints vs. Panthers | Browns vs. Steelers

Lorenzo Reyes: Panthers 18, Saints 17

The reason why I like the Panthers here is their pass rush. The Saints gave up four sacks and Carolina sacked Falcons quarterback Desmond Ridder four times. Bryce Young is still learning, but if he limits turnovers he will give the Panthers a shot here. Still, I think there are better plays out there.

Tyler Dragon: Saints 24, Panthers 17

Rookie Bryce Young was shaky in his NFL regular-season debut. Derek Carr was steady in his Saints debut. The Saints have a better defense and a better collection of skill players on offense even without the suspended Alvin Kamara.

Victoria Hernandez: Saints 17, Panthers 10

Bryce Young will feel more comfortable at home and will have learned a lot from his NFL debut. But the Saints are more experienced and last week proved they have gelled enough to get a win.

Jordan Mendoza: Saints 27, Panthers 23

Derek Carr looks comfortable in his new home, and the defense takes advantage of Bryce Young trying to find his footing in the NFL.

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This article originally appeared on USA TODAY: New Orleans Saints at Carolina Panthers: Game predictions, picks, odds