Brazilian winger Antony was taken off on a stretcher in the 4-1 win over Chelsea leading to Ten Hag confirming that the blow to his ankle was “serious”.
It means he will sit out the Premier League final day at the very least, handing Sancho the chance to impress and earn his place in the FA Cup final.
Ten Hag spoke highly of the 23-year-old’s display on the right wing on Thursday night, which included the assist for Anthony Martial to make it 2-0.
“He did very well on the right side, and I think he played a very good game,” said the United boss.
“And I think Jadon Sancho was one of the players who [has made good] progress in this season. And there were many players in our squad who made good progress. I think it's a good base to build further on.”