Southgate made four changes to his starting line-up for the match with Wales – Kyle Walker, Jordan Henderson, Phil Foden and Marcus Rashford starting ahead of Kieran Trippier, Mason Mount, Bukayo Saka and Raheem Sterling.
Knockout stage fixtures
All times in GMT
England vs Senegal: Sunday, December 4, Al Bayt Stadium at 7pm GMT (10pm local time and 2pm ET)
World Cup schedule
Winning Group B sets up a last-16 tie against Senegal, the Afcon winners, who came second behind Holland in Group A. The match will take place on December 4, with kick off at 7pm GMT.
France topped Group D - just - and will face Poland to win the chance to face England in the quarter-finals, should Southgate's men make it out of the last-16 knock-out round.
The first two quarter-finals will take place on Friday, December 9, at 3pm and 7pm, and will be played at Education City Stadium and Lusail Iconic Stadium. The remaining quarter-finals are on Saturday, December 10, at 3pm and 7pm, and will be played at Al Thumama Stadium and Al Bayt Stadium.
The semi-finals will take place on Tuesday, December 13 and Wednesday, December 14, at Lusail Iconic Stadium and Al Bayt Stadium, with both matches taking place at 7pm.
The World Cup final will take place on Sunday, December 18 at 3pm at Lusail Iconic Stadium.
Group B results
Who is in the England squad?
Southgate named a 26-man squad for the tournament, including call-ups for James Maddison and Conor Gallagher.
Could an England player win the Golden Boot?
Very possibly. Marcus Rashford looks the most likely candidate.
Ben White has left England's squad for personal reasons and is set to miss the rest of the World Cup.
The Arsenal centre-back missed the Group B win over Wales on Monday through illness after being an unused substitute against Iran and USA.
"Ben White has left England’s training base in Al Wakrah and returned home for personal reasons," read a statement from the Football Association.
"The Arsenal defender is not expected to return to the squad for the remainder of the tournament. We ask that the player’s privacy is respected at this moment in time."
White was rewarded for his form with the Premier League leaders this season with a place in Gareth Southgate’s 26-man squad for Qatar, with his versatility at being playing right-back and centre-back making him a useful addition to the squad.
It was in March when he played against Ivory Coast and was shifted to right-back during the match, which was his last cap for England.
After arriving in Doha he spoke about how he was relishing taking the next step up after loans in the lower leagues during his time at Brighton, then playing regularly in the top-flight and earning a move to Arsenal.
“I think it is something which has continued in my career. I believe in myself. I have worked hard to get here. I don’t think I have done it an easy way. I think it is just being consistent, believing in what I do,” he said at the time.