Yahoo Sports Denver Broncos at Buffalo Bills: Predictions, picks and odds for NFL Week 10 game
The Denver Broncos (3-5) come off their bye and a historic victory to take on the Buffalo Bills (5-4) to close out Week 10 on Monday night.
The Broncos beat the Kansas City Chiefs in Week 8, snapping a 16-game losing streak. Denver's defense forced Patrick Mahomes and company to commit five turnovers. Russell Wilson has thrown for 1,613 yards this season and has one of the better touchdown-to-interception ratios in the league with 16 scores and 4 picks.
The Bills are coming off 24-18 road loss to the Cincinnati Bengals. Josh Allen went 26-of-38 for 258 yards, a touchdown and an interception. He also was Buffalo's leading rusher with 8 carries for 44 yards and a score on the ground. He's fourth in the league with 2,423 passing yards.
Will the Broncos have enough momentum to capture the road win? Or will the Bills hold them off at home?
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Bills vs. Broncos odds, moneyline, over/under
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Spread: Bills (-7.5)
Moneyline: Bills (-400); Broncos (+310)
Over/under: 46.5
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NFL Week 10 odds, predictions and picks
Bears vs. Panthers | Patriots vs. Colts | Ravens vs. Browns | Bengals vs. Texans | Jaguars vs. 49ers | Vikings vs. Saints | Steelers vs. Packers | Buccaneers vs. Titans | Cardinals vs. Falcons | Chargers vs. Lions | Cowboys vs. Giants | Seahawks vs. Commanders | Raiders vs. Jets | Bills vs. Broncos
Lorenzo Reyes: Bills 25, Broncos 21
At some point, the Bills will need to figure this out, but failing to cover any of their last five games is a big concern. Denver was also on its bye and has been much improved, especially on defense, over the last month. If Buffalo cannot establish its rushing game, I think the Broncos keep this close.
Tyler Dragon: Bills 25, Broncos 20
Buffalo’s shortcomings were highlighted in Cincinnati. The Bills’ defense is banged up and the offense lacks playmakers outside of Josh Allen and Stefon Diggs. The Broncos have won two in a row, including a huge win versus Kansas City. But the Bills are 3-0 playing at Highmark Stadium this season.
Safid Deen: Bills 27, Broncos 17
This game might be closer than we imagine with the Broncos earning some respect after their win over the Chiefs in Week 8. But the Bills are still the Bills, a perennial playoff contender despite their recent slide. Buffalo gets right at home this week against Denver.
Victoria Hernandez: Broncos 27, Bills 24
The Bills defense let Joe Burrow scamper all over them in a road loss last week and return home to hopefully contain Russell Wilson, who scored three touchdowns in a statement win before the bye. The Broncos forced Patrick Mahomes and the Chiefs to commit five turnovers in the game and will be hungry to pick apart an inconsistent Josh Allen.
Jordan Mendoza: Bills 31, Broncos 23
Can the Bills stop making mistakes? A Denver team coming off a bye and a win over the Chiefs will give Buffalo a scare, but trying to win there in primetime will be tough. The Bills pull away in the second half but this game ends up being a one-score game.
You can view the full list of USA TODAY's NFL expert predictions here.
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This article originally appeared on USA TODAY: Denver Broncos at Buffalo Bills: Game predictions, picks, odds
