49ers vs. Seattle: Best anytime NFL TD scorer bets for Thanksgiving Football in Week 12

There is plenty of football to watch throughout Week 12 of the NFL season. From a Thanksgiving triple-header to a Black Friday game to Sunday's slate of games ahead of Monday Night Football, it's an exciting week for football fans.

Concluding Thursday's three-piece is an NFC West matchup between two of the teams fighting for the top of the division: the Seattle Seahawks (6-4) and the San Francisco 49ers (7-3). A Seahawks win would put them in first place, while the 49ers can maintain their hold on the division with a victory of their own.

Here's what to know going into Thursday night's game.

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Seahawks vs. 49ers: How to watch Thanksgiving football game

When: Thursday, Nov. 23, 8:20 p.m. ET

Where: Lumen Field, Seattle, Wash.

Cable TV: NBC

Streaming: Peacock; YouTube TV; FuboTV

How to watch: Don't miss any football action with a Fubo subscription

Week 12 Thursday Night Football: Anytime touchdown scorer odds

All odds courtesy of DraftKings as of Wednesday evening.

San Francisco 49ers:

• RB Christian McCaffrey (-225)

• WR Brandon Aiyuk (+145)

• TE George Kittle (+150)

• WR Deebo Samuel (+150)

• 49ers DEF/ST (+370)

• QB Brock Purdy (+450)

Seattle Seahawks:

• RB Zach Charbonnet (+130)

• WR DK Metcalf (+230)

• WR Tyler Lockett (+260)

• WR Jaxon Smith-Njigba (+295)

• WR Jake Bobo (+600)

Best anytime touchdown bets for Week 12 Thursday Night Football

San Francisco 49ers:

RB Christian McCaffrey (-225):

This is far from the best bang-for-your-buck value to get on any bet, especially an anytime touchdown bet, but there's a reason for that. McCaffrey has scored a touchdown in all but one of his last 19 games: a Week 10 49ers victory over the Jaguars. There's no such thing as a certainty for a bet like this, but McCaffrey is as close to a certainty as one can get.

WR Brandon Aiyuk (+145):

Deebo Samuel gets a lot of attention for all of his athleticism, but Aiyuk is the 49ers' top wide receiver in yards and touchdown catches. He's currently on a two-game streak of games with a touchdown catch, and it's easier to see him adding another one than George Kittle. The Seahawks have allowed 10 touchdowns to wide receivers but just one to a tight end.

QB Brock Purdy (+450):

Fun fact: in both of Purdy's previous matchups with the 49ers' other NFC West opponents, he's scored a rushing touchdown. It's not a common scenario – the young quarterback only has two rushing scores on the season – with such a great running back sharing the backfield. With the odds Purdy's getting (higher than his team's defense/special teams!), it might be worth sprinkling an investment on him keeping his rushing TD streak going against divisional opponents.

Seattle Seahawks:

RB Zach Charbonnet (+130):

The rookie has yet to score a touchdown in his career, but that has far more to do with his splitting of backfield duties with Kenneth Walker than a lack of skill on his part. I expect Seattle to try to get Charbonnet his first career score with Walker likely out with an oblique injury suffered in Week 11.

WR DK Metcalf (+230):

Metcalf has scored a touchdown in both divisional games he's been healthy for this season. Tyler Lockett's nagging hamstring injury may create more reliance on Metcalf to carry the receiving game in Week 12.

WR Jake Bobo (+600):

Take your pick between Jaxon Smith-Njigba (+280) and Bobo here. With some slight uncertainty on Geno Smith's availability in Week 12 following a triceps injury on Sunday, it could create opportunities for other receivers to get connected with backup quarterback Drew Lock.

Bobo and Smith-Njigba both have just two touchdowns this season, but Bobo has much higher odds thanks to far fewer targets. He's a high-risk, high-reward bet here, but so is Smith-Njigba (with lower odds).

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Thursday Night Football: odds, betting lines for 49ers at Seahawks on Thanksgiving

The 49ers are favorites to defeat the Seahawks, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.

All odds as of Wednesday evening.

• Spread: 49ers (-7.5)

• Moneyline: 49ers (-375); Seahawks (+290)

• Over/under: 44

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This article originally appeared on USA TODAY: TNF Week 12: anytime touchdown odds, top bets for Thanksgiving night