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Darrelle Revis, Reggie Bush, C.J. Spiller have the key injuries from Week 3

This could be a major hit for the New York Jets. (AP)

The two biggest injury stories of the upcoming week both occurred at Sun Life Stadium, where New York Jets cornerback Darrelle Revis and Miami Dolphins running back Reggie Bush each exited with left knee injuries. Of the two, Revis' injury appears to be much more serious. Citing a team source, Jason Cole of Yahoo! Sports reports that the All-Pro cornerback "probably has a torn ACL," but the official diagnosis will not be known until after an MRI on Monday. Armando Salguero of the Miami Herald reports that Bush's injury is not season-ending.

Staying in the AFC East, Buffalo Bills running back C.J. Spiller went down with a left shoulder injury in the first quarter of the Bills' 24-14 win over the Cleveland Browns. Spiller, who led the NFL in rushing entering Sunday's action, had four carries for 16 yards and two receptions for 42 yards, including a 32-yard touchdown, prior to his injury, which Mike Florio of ProFootballTalk.com reports is a sprained shoulder that will keep him out for two weeks. The Bills could possibly get Fred Jackson (knee) back for next week's game against the New England Patriots.

[Related: Belichick grabs at official after loss to Ravens]

Quarterback Matthew Stafford was unavailable to the Detroit Lions during the final moments of their 44-41 loss to the Tennessee Titans after suffering a strained muscle in his right leg in the fourth quarter. Stafford will undergo an MRI on Monday and his availability for next Sunday's game against the Minnesota Vikings is unknown. The Lions are off the following week, so if it's iffy, and if they think they can get back to .500 with Shaun Hill — who valiantly led the team back from 14 points down to force overtime on Sunday — as the starter, they may elect to give Stafford the additional time to get back to 100 percent for the final 12 weeks of the regular season.

Gruesome injury for Houston Texans quarterback Matt Schaub, who lost a piece of his left ear after taking a vicious shot from Denver Broncos linebacker Joe Mays that knocked Schaub's helmet off early in the third quarter. Schaub had to sit out one play, but doctors did not observe any concussion symptoms and he was allowed to return on the same possession. Later in the third quarter, Schaub hit tight end Owen Daniels for his fourth touchdown pass of the game.

The scariest injury scene on Sunday involved Oakland Raiders wide receiver Darrius Heyward-Bey, who was knocked unconscious and carted off the field during the Raiders' 34-31 win over the Pittsburgh Steelers. Heyward-Bey took a helmet-to-helmet hit from Steelers safety Ryan Mundy (who did not intend to make such vicious contact and was not penalized on the play) and was taken to a local hospital for observation. The fourth-year wideout was able to lift his arm to give a thumbs up to the crowd on his way off the field. While it's far too early to speculate on Heyward-Bey's injury and time frame for a return to the field, it is worth noting that Heyward-Bey was removed from the playing field on a stretcher with his neck immobilized last Nov. 20 and played the following week.

[Related: Falcons moving up the chart in week 3's winners/losersl

Already playing without 2011 second-round defensive end Da'Quan Bowers (Achilles), the Tampa Bay Buccaneers may have lost 2011 first-round defensive end Adrian Clayborn, who may have suffered a season-ending injury to his right knee in Sunday's 16-10 loss to the Dallas Cowboys. In that same game, the Cowboys lost starting safety Barry Church for the season to an Achilles injury. That forced the Cowboys to shuffle their secondary, with $50.1 million free-agent cornerback Brandon Carr moving to safety. Wide receiver Miles Austin suffered bruised ribs but was able to play through the injury.

Another former first-round pick dealing with a right knee injury is Washington Redskins left tackle Trent Williams, who was hurt early in the team's 38-31 loss to the Cincinnati Bengals. Williams returned to the game briefly in the second half but had trouble moving to his right and was replaced by Jordan Black for the remainder of the game.

Indianapolis Colts wide receiver Austin Collie made his 2012 debut on Sunday after being held out of the first two weeks with concerns over a concussion he sustained during the preseason. Collie was targeted one time, coming down with a 6-yard reception, but suffered a right knee injury that head coach Chuck Pagano described as "serious" after the game, according to the Indianapolis Star.

Tennessee Titans wide receiver Kenny Britt (ankle) and tight end Jared Cook (shoulder) were both injured on Sunday, but neither injury is believed to be too serious. Britt caught six passes for 55 yards in his second game back from a suspension, while Cook had a 61-yard touchdown on Sunday. According to John Glenn of The Tennessean, head coach Mike Munchak expects Cook to play next week.

The Kansas City Chiefs broke into the win column for the first time this season, but it may have come with a hefty price tag. Starting center Rodney Hudson left in the third quarter with a knee injury, while wide receiver Dexter McCluster suffered an elbow injury. How long both players will be out are matters that will be determined early this week.

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