| | P | Non-roster Invitee (The St. Louis Cardinals signed LHP Andrew Suárez to a minor league contract with an invitation to spring training.) |
| | C | Non-roster Invitee (The St. Louis Cardinals signed C Tres Barrera to a minor league contract with an invitation to spring training.) |
| | P | Drafted Via Rule 5 (Signed) |
| | C | Signed as Free Agent (five-year contract) |
| | P | Signed as Free Agent (one-year contract) |
| | 3B | Signed to a Minor League Contract (Signed) |
| | RF | Signed to a Minor League Contract (Signed) |
| | RF | Signed to a Minor League Contract (Signed) |
| | CF | Free Agent - No Contract Offer (non-tendered) |
| | P | Free Agent - No Contract Offer (non-tendered) |
| | P | Signed (avoids arbitration) |
| | P | Purchased From Minors (Signed) |
| | P | Declared Free Agency (Signed) |
| | SS | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | RP | Declared Free Agency (Signed) |
| | RF | Declared Free Agency (Signed) |
| | C | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | 3B | Declared Free Agency (Signed) |
| | C | Declared Free Agency (Signed) |
| | 1B | Declared Free Agency (INF Dariel Gomez declared free agency.) |
| | C | Retired (Signed) |
| | C | Declared Free Agency (Signed) |
| | 1B | Retired (Signed) |
| | 1B | Declared Free Agency (Signed) |
| | SS | Purchased From Minors (Signed) |
| | SS | Traded (for cash considerations) From |
| | LF | Purchased From Minors (Signed) |
| | LF | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | SS | Outrighted to Minors (Signed) |
| | P | Outrighted to Minors (Signed) |
| | P | Signed (one-year extension) |
| | P | Released (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | SS | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | 2B | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | C | Called Up from Minors (Signed) |
| | LF | Removed From 10-Day IL (Strained left hamstring) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Signed (two-year contract extension) |
| | P | Sent to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | 2B | Sent to Minors (Signed) |
| | LF | Called Up from Minors (Signed) |
| | LF | Placed on 10-Day IL (Strained left hamstring) |
| | CF | Removed From 10-Day IL (Sprained left thumb) |
| | P | Recalled From Minors Rehab (Signed) |
| | CF | Recalled From Minors Rehab (Signed) |
| | P | Return of 27th man (Signed) |
| | P | Called Up from Minors (recalled as 29th roster player) |
| | CF | Sent to Minors for Rehabilitation (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | LF | Acquired Off Waivers (Signed) To |
| | RF | Purchased From Minors (Signed) |
| | CF | Placed on 10-Day IL (Sprained left thumb) |
| | LF | Designated for Assignment (Signed) |
| | P | Acquired Off Waivers (Signed) To |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Designated for Assignment (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Released (Signed) |
| | CF | Purchased From Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | 3B | Reinstated from Paternity Leave List (Signed) |
| | LF | Sent to Minors (Signed) |
| | P | Reinstated From Restricted List (Signed) |
| | P | Sent to Minors (Signed) |
| | LF | Called Up from Minors (Signed) |
| | 3B | Placed on Paternity Leave List (Signed) |
| | CF | Transferred to 60-Day IL (Right foot plantar fasciitis) |
| | P | Called Up from Minors (recalled as 27th roster player) |
| | P | Return of 27th man (Signed) |
| | C | Reinstated From Restricted List (Signed) |
| | C | Sent to Minors (Signed) |
| | P | Placed on Restricted List (Signed) |
| | P | Reinstated from Paternity Leave List (Signed) |
| | C | Called Up from Minors (Signed) |
| | C | Placed on Restricted List (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Placed on Paternity Leave List (Signed) |
| | LF | Recalled From Minors Rehab (Signed) |
| | LF | Sent to Minors (Signed) |
| | LF | Removed From 10-Day IL (Right forearm strain) |
| | P | Signed to a Minor League Contract (Signed) |
| | P | Released (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Designated for Assignment (Signed) |
| | P | Called Up from Minors (Signed) |
| | LF | Sent to Minors for Rehabilitation (Signed) |
| | P | Transferred to 60-Day IL (Right hip surgery - out for season) |
| | SS | Sent to Minors (Signed) |
| | SS | Acquired Off Waivers (Signed) From |
| | P | Return of 27th man (Signed) |
| | P | Called Up from Minors (recalled as 27th roster player) |
| | P | Sent to Minors (Signed) |
| | CF | Traded (for LHP Jordan Montgomery) To |
| | CF | Recalled From Minors Rehab (Signed) |
| | P | Traded (for OF Harrison Bader) From |
| | C | Traded (for cash considerations) To |
| | C | Recalled From Minors Rehab (Signed) |
| | C | Traded (For RHP Carlos Guarate) From |
| | P | Sent to Minors (Signed) |
| | C | Removed From 10-Day IL (Right knee inflammation) |
| | P | Traded (for LHP Jose Quintana, four-player deal) To |
| | P | Traded (for RHP Johan Oviedo, four-player deal) From |
| | P | Traded (for RHP Johan Oviedo, four-player deal) From |
| | C | Designated for Assignment (Signed) |
| | 3B | Traded (for LHP Jose Quintana, four-player deal) To |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Sent to Minors (Signed) |
| | SS | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Traded (for INF Edmundo Sosa) From |
| | SS | Traded (for LHP JoJo Romero) To |
| | 3B | Reinstated From Restricted List (Signed) |
| | 1B | Reinstated From Restricted List (Signed) |
| | C | Reinstated From Restricted List (Signed) |
| | LF | Sent to Minors (return of Replacement Player) |
| | C | Sent to Minors (return of Replacement Player) |
| | 3B | Outrighted to Minors (return of Replacement Player) |
| | C | Sent to Minors for Rehabilitation (Signed) |
| | 3B | Purchased From Minors (selected as Replacement Player) |
| | C | Called Up from Minors (recalled as Replacement Player) |
| | LF | Called Up from Minors (recalled as Replacement Player) |
| | C | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | 1B | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | 3B | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | CF | Sent to Minors for Rehabilitation (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | LF | Placed on 10-Day IL (Right forearm strain) |
| | P | Called Up from Minors (Signed) |
| | RF | Called Up from Minors (Signed) |
| | RF | Sent to Minors (Signed) |
| | LF | Removed From 10-Day IL (Right hamstring strain) |
| | LF | Recalled From Minors Rehab (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Signed to Play in Korea (Doosan Bears) |
| | P | Acquired Off Waivers (Signed) To |
| | P | Released (Signed) |
| | P | Removed From 10-Day IL (COVID-19 injured list (positive test)) |
| | P | Transferred to 60-Day IL (Strained right shoulder) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Sent to Minors (Signed) |
| | LF | Removed From 10-Day IL (Strained left calf) |
| | LF | Recalled From Minors Rehab (Signed) |
| | LF | Sent to Minors (Signed) |
| | P | Designated for Assignment (Signed) |
| | P | Removed From 10-Day IL (COVID-19 injured list (positive test)) |
| | P | Sent to Minors (Signed) |
| | P | Released (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | LF | Sent to Minors for Rehabilitation (Signed) |
| | C | Sent to Minors (Signed) |
| | C | Purchased From Minors (Signed) |
| | P | Designated for Assignment (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
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