Champions Chelsea visit London rivals Spurs while leaders Manchester United host fifth-placed Everton.
Since taking the helm in 2011, Simeone has transformed Atletico into a force to be reckoned with, challenging the dominance of Real Madrid and Barcelona. Under his leadership, the club has won two La Liga titles (2014, 2021), two Europa League titles (2012, 2018), and reached two Champions League finals (2014, 2016). Despite this success, Simeone's future at Atletico remains uncertain, with reports suggesting he may be open to a new challenge. "We're sad not to still be in the Copa and Champions League, but I'm at peace, and that's the best a person can ask for," said Simeone.
Can Sean Dyche lead Everton to victory in his first match against the Premier League leaders?