| | S | Cut (Signed) |
| | C | Signed (Signed) |
| | T | Signed/draft choice (Four-year contract (through 2025)) |
| | C | Signed/draft choice (Four-year contract (through 2025)) |
| | RB | Signed/draft choice (Four-year contract (through 2025)) |
| | DT | Signed/draft choice (Four-year contract (through 2025)) |
| | RB | Signed (Signed) To |
| | QB | Cut (Signed) |
| | CB | Signed/draft choice (Four-year contract (through 2025)) |
| | C | Cut (Signed) |
| | QB | Traded (w/ pick for 2023 sixth-round draft pick) To |
| | TE | Acquired from waiver (Signed) From |
| | C | Signed (Signed) |
| | CB | Signed (Signed) |
| | T | Signed (Signed) |
| | DT | Signed (Signed) |
| | DE | Signed (Signed) |
| | QB | Signed (Signed) |
| | P | Signed (Signed) |
| | S | Signed (Signed) |
| | LB | Signed (Signed) To |
| | LB | Cut (Signed) |
| | RB | Cut (Signed) |
| | WR | Team declines option (Fifth-year option on rookie contract) |
| | DT | Re-signed/unrest FA (One-year contract (through 2022)) |
| | LB | Signed/unrest FA (One-year contract (through 2022)) To |
| | WR | Traded (w/ pick for 2023 third-round draft pick) From |
| | S | Signed/unrest FA (One-year contract (through 2022)) From |
| | CB | Signed (Two-year contract (through 2023)) From |
| | T | Re-signed/unrest FA (Two-year contract (through 2023)) |
| | LB | Re-signed/unrest FA (Two-year contract (through 2023)) |
| | WR | Signed/unrest FA (Two-year contract (through 2023)) To |
| | K | Re-signed/unrest FA (Two-year contract (through 2023)) |
| | RB | Signed/unrest FA (Two-year contract (through 2023)) To |
| | C | Signed/unrest FA (Three-year contract (through 2024)) To |
| | CB | Signed/unrest FA (Five-year contract (through 2026)) To |
| | WR | Signed/unrest FA (Two-year contract (through 2023)) From |
| | C | Declared Free Agent (Signed) |
| | C | Traded (for 2022 fifth-round pick) To |
| | CB | Declared Free Agent (Signed) |
| | WR | Restricted Free Agent (Signed) |
| | RB | Signed/unrest FA (One-year contract (through 2022)) To |
| | DE | Traded (for LB Mack Wilson) To |
| | RB | Declared Free Agent (Signed) |
| | LB | Traded (for DE Chase Winovich) From |
| | LB | Declared Free Agent (Signed) |
| | TE | Declared Free Agent (Signed) |
| | K | Declared Free Agent (Signed) |
| | DT | Declared Free Agent (Signed) |
| | LB | Declared Free Agent (Signed) |
| | T | Declared Free Agent (Signed) |
| | CB | Signed (One-year contract (through 2022)) From |
| | RB | Declared Free Agent (Signed) |
| | WR | Declared Free Agent (Signed) |
| | LB | Declared Free Agent (Signed) |
| | LB | Declared Free Agent (Signed) |
| | RB | Re-signed (Two-year contract (through 2023)) |
| | C | Re-signed (One-year contract (through 2022)) |
| | QB | Re-signed (Two-year contract (through 2023)) |
| | WR | Re-signed (One-year contract (through 2022)) |
| | S | Re-signed (One-year contract (through 2022)) |
| | LB | Cut (Signed) |
| | G | Signed (Signed) |
| | CB | Signed (Signed) To |
| | DE | Activated from PUPL (Signed) |
| | LB | Activated from PUPL (Signed) |
| | DT | Signed (Signed) |
| | CB | Signed (Signed) To |
| | DT | Signed (Signed) |
| | G | Pract. squad del (Signed) |
| | DT | Pract. squad del (Signed) |
| | CB | Pract. squad del (Signed) |
| | TE | Pract. squad del (Signed) |
| | C | Pract. squad del (Signed) |
| | DT | Pract. squad del (Signed) |
| | S | Pract. squad del (Signed) |
| | CB | Pract. squad del (Signed) |
| | WR | Pract. squad del (Signed) |
| | CB | Pract. squad del (Signed) |
| | CB | Pract. squad del (Signed) |
| | LB | Pract. squad del (Signed) |
| | G | Signed (Signed) From |
| | WR | Signed (Signed) From |
| | K | Signed (Signed) |
| | WR | Pract. squad add (Signed) |
| | WR | Signed (Signed) |
| | CB | Pract. squad add (Signed) |
| | CB | Reinstated (Signed) |
| | DT | Pract. squad add (Signed) |
| | S | Reinstated (Signed) |
| | CB | Pract. squad add (Signed) |
| | WR | Signed (Signed) |
| | T | Signed (Signed) |
| | RB | Signed (Signed) |
| | WR | Active/prac. squad (Signed) |
| | CB | Active/prac. squad (COVID-19 Replacement) |
| | DT | Active/prac. squad (COVID-19 Replacement) |
| | CB | Active/prac. squad (Signed) |
| | T | Reinstated (Signed) |
| | CB | Pract. squad add (Signed) From |
| | T | Pract. squad add (Signed) |
| | S | Reserve/non football injury (COVID-19) |
| | CB | Reinstated (Signed) |
| | WR | Pract. squad add (Signed) From |
| | CB | Pract. squad add (Signed) From |
| | DT | Pract. squad add (Signed) |
| | S | Pract. squad add (Signed) |
| | CB | Pract. squad add (Signed) |
| | CB | Reserve/non football injury (COVID-19) |
| | CB | Active/prac. squad (COVID-19 Replacement) |
| | DT | Active/prac. squad (COVID-19 Replacement) |
| | S | Active/prac. squad (Signed) |
| | LB | Pract. squad add (Signed) From |
| | WR | Pract. squad add (Signed) |
| | CB | Pract. squad add (Signed) |
| | DT | Pract. squad add (Signed) |
| | T | Pract. squad del (COVID-19) |
| | CB | Reserve/non football injury (COVID-19) |
| | LB | Reinstated (Signed) |
| | S | Re-signed (Three-year extension (through 2024)) |
| | WR | Active/prac. squad (Signed) |
| | LB | Reinstated (Signed) |
| | CB | Active/prac. squad (Signed) |
| | QB | Reinstated (Signed) |
| | DT | Active/prac. squad (COVID-19 Replacement) |
| | LB | Reinstated (Signed) |
| | LB | Reinstated (Signed) |
| | T | Reserve/non football injury (COVID-19) |
| | DE | Reinstated (Signed) |
| | LB | Reinstated (Signed) |
| | RB | Reinstated (Signed) |
| | LB | Reserve/non football injury (COVID-19) |
| | LB | Reinstated (Signed) |
| | LB | Reserve/non football injury (COVID-19) |
| | LB | Reinstated (Signed) |
| | G | Reinstated (Signed) |
| | QB | Reserve/non football injury (COVID-19) |
| | LB | Reserve/non football injury (COVID-19) |
| | LB | Reserve/non football injury (COVID-19) |
| | WR | Pract. squad add (Signed) |
| | CB | Pract. squad add (Signed) |
| | DT | Pract. squad add (Signed) |
| | DT | Active/prac. squad (COVID-19 Replacement) |
| | DE | Reserve/non football injury (COVID-19) |
| | P | Active/prac. squad (Signed) To |
| | CB | Active/prac. squad (Signed) |
| | WR | Reinstated (Signed) |
| | WR | Active/prac. squad (COVID-19 Replacement) |
| | RB | Reserve/non football injury (COVID-19) |
| | RB | Reinstated (Signed) |
| | TE | Reinstated (Signed) |
| | RB | Pract. squad add (Signed) |
| | C | Pract. squad add (Signed) |
| | DT | Pract. squad add (Signed) |
| | LB | Reserve/non football injury (COVID-19) |
| | LB | Reserve/non football injury (COVID-19) |
| | LB | Reserve/non football injury (COVID-19) |
| | WR | Reserve/non football injury (COVID-19) |
| | C | Pract. squad add (Signed) To |
| | RB | Active/prac. squad (Signed) |
| | C | Active/prac. squad (COVID-19 Replacement) |
| | DT | Active/prac. squad (COVID-19 Replacement) |
| | QB | Active/prac. squad (Signed) To |
| | DT | Signed (Signed) To |
| | G | Reserve/non football injury (COVID-19) |
| | CB | Pract. squad add (COVID-19) To |
| | LB | Acquired from waiver (Signed) To |
| | G | Pract. squad del (Signed) |
| | LB | Cut (Signed) |
| | S | Reinstated (Signed) |
| | S | Reinstated (Signed) |
| | TE | Reserve/non football injury (COVID-19) |
| | DT | Pract. squad add (Signed) To |
| | T | Pract. squad add (Signed) To |
| | TE | Pract. squad add (Signed) To |
| | DT | Pract. squad add (Signed) |
| | S | Pract. squad add (Signed) |
| | S | Active/prac. squad (Signed) |
| | DT | Active/prac. squad (COVID-19 Replacement) |
| | K | Pract. squad add (Signed) |
| | S | Pract. squad add (Signed) To |
| | S | Reserve/non football injury (COVID-19) |
| | CB | Pract. squad del (Signed) |
| | K | Cut (Signed) |
| | DT | Pract. squad del (Signed) |
| | RB | Pract. squad add (Signed) From |
| | CB | Pract. squad add (Signed) From |
| | RB | Reserve/non football injury (COVID-19) |
| | DT | Pract. squad add (Signed) From |
| | DE | Active/prac. squad (Signed) To |
| | P | Pract. squad add (Signed) From |
| | WR | Pract. squad add (Signed) To |
| | CB | Pract. squad add (Signed) To |
| | WR | Cut (Signed) |
| | K | Active/prac. squad (Signed) To |
| | TE | Pract. squad add (Signed) |
| | DE | Pract. squad add (Signed) |
| | TE | Active/prac. squad (Signed) |
| | DE | Active/prac. squad (Signed) |
| | QB | Signed (Signed) To |
| | C | Pract. squad add (Signed) |
| | CB | Pract. squad del (Signed) |
| | QB | Activated from PUPL (Signed) |
| | TE | Pract. squad del (Signed) |
| | WR | Pract. squad add (Signed) |
| | C | Pract. squad del (Signed) |
| | C | Cut (Signed) |
| | WR | Active/prac. squad (Signed) |
| | WR | Pract. squad add (Signed) To |
| | DT | Pract. squad add (Signed) |
| | DT | Active/prac. squad (Signed) |
| | CB | Pract. squad add (Signed) From |
| | LB | Active/prac. squad (Signed) From |
| | CB | Pract. squad add (Signed) From |
| | C | Active/prac. squad (Signed) |
| | S | Pract. squad del (Signed) |
| | DE | Pract. squad add (Signed) To |
| | LB | Pract. squad add (Signed) To |
| | C | Pract. squad add (Signed) |
| | DT | Pract. squad add (Signed) |
| | C | Active/prac. squad (Signed) |
| | DT | Active/prac. squad (Signed) |
| | K | Pract. squad add (Signed) From |
| | CB | Active/prac. squad (Signed) |
| | C | Pract. squad add (Signed) |
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