| | DB | Placed on Injured Reserve (The New England Patriots placed DB Marcus Jones on the IR.) |
| | QB | Signed (The New England Patriots signed QB Will Grier to the active squad from the Cincinnati Bengals practice squad.) From |
| | CB | Pract. squad add (The New England Patriots signed DB Azizi Hearn to the practice squad.) |
| | CB | Pract. squad add (The New England Patriots signed DB Breon Borders to the practice squad.) |
| | QB | Pract. squad add (The New England Patriots signed QB Matt Corral to the practice squad.) |
| | LB | Signed (The Denver Broncos signed LB Ronnie Perkins.) To |
| | WR | Pract. squad add (The New England Patriots assigned WR Jalen Reagor to the practice squad.) |
| | QB | Released (The New England Patriots released QB Matt Corral. ) |
| | LB | Pract. squad add (The New England Patriots assigned LB Calvin Munson to the practice squad.) |
| | QB | Released (The New England Patriots released QB Ian Book. ) |
| | LB | Activated (The New England Patriots elevated LB Calvin Munson to the active roster. ) |
| | WR | Activated (The New England Patriots elevated WR Jalen Reagor to the active roster. ) |
| | QB | Pract. squad add (The New England Patriots signed QB Ian Book to the practice squad.) |
| | CB | Pract. squad add (The New England Patriots signed CB William Hooper to the practice squad.) |
| | LB | Pract. squad add (The New England Patriots assigned LB Calvin Munson to the practice squad.) |
| | WR | Signed (The New England Patriots signed WR Ty Montgomery to the active roster.) |
| | QB | Exempt/Commissioner's Permission List (The New England Patriots placed QB Matt Corral on the exempt/left squad list.) |
| | LB | Activated (The New England Patriots elevated LB Calvin Munson from the practice squad.) |
| | DB | Placed on Injured Reserve (The New England Patriots placed DB Jack Jones on injured reserve.) |
| | QB | Activated (The England Patriots activated QB Bailey Zappe from the practice squad.) |
| | OL | Waived Injury (The New England Patriots waived OL Conor McDermott due to injury.) |
| | OL | Placed on Injured Reserve (The New England Patriots placed OL Riley Reiff on Injured Reserve. ) |
| | DL | Pract. squad add (The New England Patriots signed DL Jeremiah Pharms Jr. to the practice squad. ) |
| | TE | Activated (The New England Patriots elevated TE Pharaoh Brown to the active roster. ) |
| | WR | Pract. squad add (The New England Patriots signed WR T.J. Luther to the practice squad.) |
| | WR | Released (The New England Patriots released WR Thyrick Pitts from the practice squad.) |
| | P | Pract. squad add (The New England Patriots signed P Corliss Waitman to the practice squad.) |
| | QB | Claimed (The New England Patriots claimed QB Matt Corral off waivers.) |
| | OL | Pract. squad add (The New England Patriots signed OL Kody Russey to the practice squad.) |
| | WR | Pract. squad add (The New England Patriots signed WR Jalen Reagor to the practice squad.) |
| | WR | Placed on Injured Reserve (The New England Patriots placed WR Tyquan Thornton on IR.) |
| | LB | Pract. squad add (The New England Patriots signed LB Ronnie Perkins to the practice squad.) |
| | LB | Pract. squad add (The New England Patriots signed LB Joe Giles-Harris to the practice squad.) |
| | TE | Pract. squad add (The New England Patriots signed TE Matt Sokol to the practice squad.) |
| | OL | Pract. squad add (The New England Patriots signed OL James Ferentz to the practice squad.) |
| | WR | Pract. squad add (The New England Patriots signed RB Ty Montgomery to the practice squad.) |
| | LB | Pract. squad add (The New England Patriots signed LB Calvin Munson to the practice squad.) |
| | S | Pract. squad add (The New England Patriots signed SAF Joshuah Bledsoe to the practice squad.) |
| | TE | Pract. squad add (The New England Patriots signed TE Pharaoh Brown to the practice squad.) |
| | OL | Pract. squad add (The New England Patriots signed OL Andrew Stueber to the practice squad.) |
| | WR | Pract. squad add (The New England Patriots signed WR Thyrick Pitts to the practice squad.) |
| | QB | Pract. squad add (The New England Patriots signed QB Malik Cunningham to the practice squad.) |
| | QB | Pract. squad add (The New England Patriots signed QB Bailey Zappe to the practice squad.) |
| | RB | Pract. squad add (The New England Patriots signed RB Kevin Harris to the practice squad.) |
| | CB | Placed on Injured Reserve (The New England Patriots placed CB Isaiah Bolden on Injured Reserve.) |
| | WR | Waived (The New England Patriots waived WR Raleigh Webb.) |
| | LB | Released (The New England Patriots released LB Ronnie Perkins.) |
| | OL | Waived (The New England Patriots waived OL Bill Murray.) |
| | DL | Released (The New England Patriots released DL Jeremiah Pharms.) |
| | OL | Released (The New England Patriots released OL Andrew Stueber.) |
| | TE | Waived (The New England Patriots waived TE Matt Sokol.) |
| | S | Waived (The New England Patriots waived S Joshuah Bledsoe.) |
| | TE | Released (The New England Patriots released TE Anthony Firkser.) |
| | WR | Released (The New England Patriots released RB Ty Montgomery.) |
| | OL | Released (The New England Patriots released OL Kody Russey.) |
| | RB | Released (The New England Patriots released RB J.J. Taylor.) |
| | LB | Released (The New England Patriots released LB Calvin Munson.) |
| | QB | Waived (The New England Patriots waived QB Bailey Zappe.) |
| | LB | Released (The New England Patriots released LB Joe Giles-Harris.) |
| | QB | Waived (The New England Patriots waived QB Malik Cunningham.) |
| | RB | Released (The New England Patriots released RB Kevin Harris.) |
| | OL | Activated (The New England Patriots activated OL Calvin Anderson.) |
| | WR | Waived (The New England Patriots waived WR Thyrick Pitts.) |
| | K | Traded (The New England Patriots traded K Nick Folk to the Tennessee Titans.) To |
| | OL | Released (The New England Patriots released OL Chasen Hines.) |
| | OL | Released (The New England Patriots released OL James Ferentz.) |
| | OL | Placed on Injured Reserve (The New England Patriots placed OL Conor McDermott on Injured Reserve.) |
| | QB | Released (The New England Patriots released QB Trace McSorley.) |
| | P | Released (The New England Patriots released P Corliss Waitman.) |
| | T | Traded (The Minnesota Vikings traded OL Vederian Lowe to the New England Patriots.) From |
| | RB | Traded (The New England Patriots traded RB Pierre Strong Jr. to the Cleveland Browns.) To |
| | OL | Released (The New England Patriots released OL Micah Vanterpool.) |
| | LB | Waived (The New England Patriots waived LB Diego Fagot.) |
| | LB | Waived (The New England Patriots waived LB Carson Wells.) |
| | TE | Released (The New England Patriots released TE Jonny Lumpkin.) |
| | DL | Waived (The New England Patriots waived DL Justus Tavai.) |
| | DB | Released (The New England Patriots released DB Rodney Randle Jr.) |
| | TE | Released (The New England Patriots released TE Scotty Washington.) |
| | RB | Released (The New England Patriots released RB CJ Marable.) |
| | DB | Waived (The New England Patriots waived DB Brad Hawkins.) |
| | T | Traded (The Cleveland Browns traded OL Tyrone Wheatley Jr. to the New England Patriots.) From |
| | DB | Waived (The New England Patriots waived DB Quandre Mosely.) |
| | DL | Released (The New England Patriots released DL Carl Davis Jr. ) |
| | WR | Placed on Injured Reserve (The New England Patriots placed WR Tre Nixon on the IR, after being waived due to injury.) |
| | DT | Waived Injury (The New England Patriots waived DL Marquan McCall.) |
| | WR | Waived (The New England Patriots waived WR Tre Nixon.) |
| | DT | Claimed (The New England Patriots claimed DT Marquan McCall off waivers from the Carolina Panthers.) From |
| | LB | Signed (The New England Patriots signed LB Carson Wells.) |
| | LS | Released (The New England Patriots released LS Tucker Addington.) |
| | DE | Released (The New England Patriots released DL DaMarcus Mitchell.) |
| | RB | Signed (The New England Patriots signed RB Ezekiel Elliott. ) |
| | LB | Waived (The New England Patriots waived LB Jourdan Heilig. ) |
| | LB | Waived (The New England Patriots waived LB Olakunle Fatukasi. ) |
| | OL | Signed (The New England Patriots signed OL Micah Vanterpool. ) |
| | RB | Signed (The New England Patriots signed RB CJ Marable. ) |
| | LB | Signed (The New England Patriots signed LB Joe Giles-Harris.) |
| | LB | Signed (The New England Patriots signed LB Trey Flowers.) |
| | LB | Placed on PUPL (The New England Patriots placed LB Trey Flowers on the physically unable to perform list. ) |
| | LB | Waived Injury (The New England Patriots waived LB Terez Hall.) |
| | LB | Placed on Injured Reserve (The New England Patriots placed LB Terez Hall on the IR, after being waived due to injury.) |
| | LB | Waived Injury (The New England Patriots waived LB Terez Hall due to injury.) |
| | WR | Waived (The New England Patriots waived WR Ed Lee.) |
| | WR | Claimed (The New England Patriots claimed WR Thyrick Pitts off waivers.) |
| | WR | Retired (The New England Patriots placed WR Jalen Hurd on the reserve-retired list.) |
| | DE | Activated (The New England Patriots activated DL DaMarcus Mitchell from the Non Football Injury-Related list.) |
| | DL | Activated (The New England Patriots activated T Justus Tavai from the physically unable to perform list.) |
| | DE | Reserve/non football injury (The New England Patriots placed LB DaMarcus Mitchell on the non-football injury list.) |
| | OL | Reserve/non football injury (The New England Patriots placed T Calvin Anderson on the non-football injury list.) |
| | WR | Signed (The New England Patriots signed WR Jalen Hurd. ) |
| | LB | Signed (The New England Patriots signed LB Diego Fagot. ) |
| | DL | Placed on PUPL (The New England Patriots placed DL Justus Tavai on the PUP list.) |
| | DB | Placed on PUPL (The New England Patriots placed DB Cody Davis on the PUP list.) |
| | OL | Placed on PUPL (The New England Patriots placed OL Mike Onwenu on the PUP list.) |
| | RB | Waived (The New England Patriots waived RB James Robinson.) |
| | CB | Waived (The New England Patriots waived DB Tae Hayes. ) |
| | DL | Re-signed (The New England Patriots re-signed DL Justus Tavai.) |
| | DL | Waived (The New England Patriots waived DL Justus Tavai.) |
| | TE | Signed (The New England Patriots signed TE Anthony Firkser.) |
| | LB | Placed on Injured Reserve (The New England Patriots placed LB Raekwon McMillan on Injured Reserve.) |
| | DL | Signed (The New England Patriots signed undrafted free agent DT Justus Tavai.) |
| | OL | Waived (The New England Patriots placed OL Yodny Cajuste on waivers.) |
| | LB | Signed (The New England Patriots signed LB Jourdan Heilig.) |
| | DL | Signed (The New England Patriots signed DL Carl Davis Jr.) |
| | TE | Signed (The New England Patriots signed TE Johnny Lumpkin.) |
| | WR | Released (The New England Patriots released WR Lynn Bowden.) |
| | CB | Signed (The New England Patriots signed CB Tae Hayes.) |
| | DB | Re-signed (The New England Patriots re-signed CB Myles Bryant.) |
| | QB | Signed (The New England Patriots signed QB Trace McSorley.) |
| | OL | Signed (The New England Patriots signed OL Yodny Cajuste.) |
| | P | Signed (The New England Patriots signed P Corliss Waitman.) |
| | DB | Re-signed (The New England Patriots re-signed DB Jalen Mills.) |
| | DB | Signed (The New England Patriots signed DB Cody Davis. ) |
| | LB | Signed (The New England Patriots signed LB Chris Board.) |
| | TE | Signed (The New England Patriots signed TE Mike Gesicki.) |
| | DB | Released (The New England Patriots released CB Jalen Mills.) |
| | LB | Re-signed (The New England Patriots re-signed LB Mack Wilson Sr.) |
| | LS | Re-signed (The New England Patriots resigned LS Joe Cardona.) |
| | WR | Signed (The New England Patriots signed WR JuJu Smith-Schuster.) |
| | OL | Signed (The New England Patriots signed OL Riley Reiff.) |
| | RB | Signed (The New England Patriots signed RB James Robinson.) |
| | OL | Signed (The New England Patriots signed OL Calvin Anderson.) |
| | DB | Signed (The New England Patriots signed SAF Jabril Peppers.) |
| | DB | Team Suspension (The New England Patriots signed DB Jonathan Jones.) |
| | LB | Signed (The New England Patriots signed LB Raekwon McMillan.) |
| | T | Declared Free Agent (OL Isaiah Wynn declared free agency.) |
| | LS | Declared Free Agent (LS Joe Cardona declared free agency.) |
| | TE | Traded (The New England Patriots traded TE Jonnu Smith to the Atlanta Falcons.) To |
| | CB | Declared Free Agent (DB Joejuan Williams declared free agency.) |
| | DB | Declared Free Agent (DB Jabrill Peppers declared free agency.) |
| | LB | Declared Free Agent (LB Mack Wilson Sr. declared free agency.) |
| | OLB | Declared Free Agent (OL Marcus Cannon declared free agency.) |
| | OL | Declared Free Agent (OL Yodny Cajuste declared free agency.) |
| | WR | Declared Free Agent (WR Jakobi Meyers declared free agency.) |
| | DB | Declared Free Agent (DB Cody Davis declared free agency.) |
| | DL | Declared Free Agent (DL Carl Davis Jr. declared free agency.) |
| | RB | Declared Free Agent (RB Damien Harris declared free agency.) |
| | WR | Declared Free Agent (WR Nelson Agholor declared free agency.) |
| | DB | Retired (S Devin McCourty has retired from the NFL.) |
| | P | Released (The New England Patriots released P Jake Bailey.) |
| | OL | Released (The New England Patriots released OL Hayden Howerton.) |
| | DT | Released (The New England Patriots released DL LaBryan Ray.) |