The Senators said the decision to cancel Monday's practice was made "for precautionary reasons."
Holden and Capuano were placed on the protocol list Sunday, a day after Ottawa played a home game against the Tampa Bay Lightning.
They joined forward Austin Watson, who entered into COVID-19 protocol Friday.
The Senators are scheduled to visit the Boston Bruins on Tuesday.
This report by The Canadian Press was first published Nov. 8, 2021.
The Canadian Press