The seven-time Bathurst 1000 champion is set to partner Stephen Grove in a two-car Grove Racing line-up.
The Australian GP support races, which include a 45-minute enduro, will mark Lowndes' first appearance in the one-make series.
However it will be his second start in a Porsche for the year, having debuted for the brand as part of the factory-backed Earl Bamber Motorsport line-up at the Bathurst 12 Hour.
“I’m really excited about the opportunity to continue with the Porsche family following the Bathurst 12 Hour,” said Lowndes.
“The Australian Grand Prix is a global stage and a great track, so I can’t wait to get back behind the wheel and compete in the Porsche Carrera Cup races.
“It will be a challenge given it’s my first outing in the category, which is highly competitive, but I’m looking forward to seeing what I can do.
“A big thanks to the Grove Group and Porsche Motorsport Australia for the opportunity.
“Once a racer always a racer – that side hasn’t changed for me, so I’m looking forward to the event and seeing what the rest of the year brings.”