Laureano went 3 for 4 with two walks, while Calhoun was 3 for 5 with a walk. Both scored three runs.
Blue Jays shortstop Bo Bichette left after five innings because of a sore right quadriceps. Bichette returned Aug. 19 after missing 16 games because of right knee tendinitis. Toronto went 8-8 without him.
Bichette went 0 for 3 before departing. He began the day leading the AL with 152 hits.
Right-hander Jay Jackson (3-1) intentionally walked Ramirez in the 11th and his wild pitch put runners at second and third before Calhoun’s double.
Laureano followed with his eighth home run.
Emmanuel Clase (2-7) got the final five outs for the Guardians.
Andrés Giménez’s two-run double in the eighth put Cleveland ahead 6-5, but Toronto tied it in the bottom half on Daulton Varsho’s RBI single.
Guerrero homered in the first off Cleveland right-hander Noah Syndergaard, his 20th. Cleveland tied it on Ramirez’s two-out homer in the third, his 21st.
Schneider put Toronto in front when he homered in the sixth, his fifth home run in 11 big league games. The rookie also homered and had three hits in Saturday’s 8-3 win.
Kikuchi allowed four runs and six hits in six innings.
Syndergaard allowed five runs and four hits in six innings against the team that drafted him in the first round in 2010.
Guardians: RHP Cal Quantrill (shoulder) allowed two runs and five hits over 7 1/3 innings in a rehab start at Triple-A Columbus on Saturday. Quantrill walked two and struck out six.
Blue Jays: Bichette grounded out in the fifth and did not run hard to first. Santiago Espinal came on defensively in the top of the sixth. … Chapman missed three games earlier this month because of his sore finger. He was injured returning a dumbbell to its rack in Toronto’s weight room. … Toronto put RHP Erik Swanson (back) on the 15-day IL and recalled Jackson from Triple-A Buffalo. Swanson left Saturday’s game in the seventh.
AP MLB: https://apnews.com/hub/mlb
Ian Harrison, The Associated Press