The shutout was DeSmith's first since April 21, 2022.
Filip Gustavsson stopped 15-of-17 shots for Minnesota (9-11-4), which had won its last eight meetings against Vancouver.
The Canucks lost three of their last five entering Thursday's game.
Meanwhile, the Wild outscored their opponents 18-5 during their win streak.
Much of the first period was one-way traffic from Minnesota, with Vancouver going without a shot until there was 6:42 remaining. The Wild outshot the Canucks 12-4 in the frame.
Hoglander opened the scoring with 1:55 left in the first for his ninth of the season. The left-winger brought the puck up ice from his own zone, cut into the slot from just above the right faceoff circle and beat Gustavsson with a wrist shot.
Blueger got in on the action 2:05 into the third period with his second of the season. After Conor Garland's pass split the Wild's defence, Blueger deked Gustavsson from in close, going backhand then forehand to beat the sprawling goaltender.
Canucks forward Philip Di Giuseppe made his return after being a healthy scratch the past two games … Vancouver's home game was its first "Firefighters’ Night" to honour firefighters' work during a historic wildfire season this past summer.
Vancouver hosts the Carolina Hurricanes on Friday.
This report by The Canadian Press was first published Dec. 7, 2023.
Nick Wells, The Canadian Press