Cincinnati (15-3, 3-2 Big East) won its second straight game after breaking a two-game losing streak at Rutgers. DePaul (10-7, 1-3) has lost four of its last five games.
Wright went down with an apparent right knee injury with 15:12 remaining. Playing defense, he had leaned toward a DePaul player when his leg gave out and he collapsed to the floor. Wright left the court and later returned to the Cincinnati bench but did not play again.
Wright had been the dominant player Tuesday, scoring his 20 points on 8-of-11 shooting and handing out seven assists. The Bearcats led by 13 points when he exited.
Cleveland Melvin led DePaul with 32 points, 10 in the last 2:03 when the Blue Demons cut a 12-point lead to three.
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