| | 2B | Signed (The Chicago White Sox signed INF Nate Mondou to a minor league contract.) |
| | P | Claimed on Unconditional Release Waivers (The Chicago White Sox claimed RHP A.J. Alexy off waivers from the Minnesota Twins.) |
| | C | Non-roster Invitee (The Chicago White Sox invited C Sebastian Rivero to spring training.) |
| | C | Non-roster Invitee (The Chicago White Sox invited C Evan Skoug to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited LHP Sammy Peralta to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited LHP Fraser Ellard to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited RHP Jesse Scholtens to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited RHP Lane Ramsey to spring training.) |
| | RF | Non-roster Invitee (The Chicago White Sox invited OF Luis Mieses to spring training.) |
| | CF | Non-roster Invitee (The Chicago White Sox invited OF Yoelqui Céspedes to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited RHP Declan Cronin to spring training.) |
| | SS | Non-roster Invitee (The Chicago White Sox invited INF Colson Montgomery to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited RHP Keynan Middleton to spring training.) |
| | SS | Non-roster Invitee (The Chicago White Sox invited INF Moises Castillo to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited RHP Edgar Navarro to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited RHP Matt Thompson to spring training.) |
| | CF | Non-roster Invitee (The Chicago White Sox invited OF Adam Haseley to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited RHP Sean Burke to spring training.) |
| | P | Non-roster Invitee (The Chicago White Sox invited LHP Andrew Perez to spring training.) |
| | C | Non-roster Invitee (The Chicago White Sox invited C Adam Hackenberg to spring training.) |
| | RF | Non-roster Invitee (The Chicago White Sox invited OF Oscar Colas to spring training.) |
| | LF | Signed to Play in Japan (Seibu Lions) |
| | P | Traded (for RHP Gregory Santos) To |
| | P | Traded (for RHP Kade McClure) From |
| | CF | Signed to a Minor League Contract (Signed) |
| | LF | Signed as Free Agent (five-year contract) |
| | C | Signed to a Minor League Contract (Signed) |
| | LF | Signed to a Minor League Contract (Signed) |
| | P | Drafted Via Rule 5 (Signed) |
| | P | Signed as Free Agent (one-year contract) |
| | LF | Signed to a Minor League Contract (Signed) |
| | LF | Free Agent - No Contract Offer (non-tendered) |
| | CF | Free Agent - No Contract Offer (non-tendered) |
| | 2B | Free Agent - No Contract Offer (non-tendered) |
| | P | Signed to a Minor League Contract (Signed) |
| | SS | Purchased From Minors (Signed) |
| | 3B | Purchased From Minors (Signed) |
| | P | Declared Free Agency (Signed) |
| | C | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | RF | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | CF | Declared Free Agency (Signed) |
| | RP | Declared Free Agency (Signed) |
| | SS | Declared Free Agency (INF Zach Remillard declared free agency.) |
| | P | Declared Free Agency (LHP Skylar Arias declared free agency.) |
| | LF | Declared Free Agency (declined player option) |
| | 2B | Declared Free Agency (team option declined) |
| | SS | Signed (team option exercised) |
| | P | Refused Minor League Assignment - Free Agent (Signed) |
| | P | Declared Free Agency (Signed) |
| | SS | Declared Free Agency (Signed) |
| | 1B | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | CF | Outrighted to Minors (Signed) |
| | P | Outrighted to Minors (Signed) |
| | CF | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | C | Removed from 7-Day IL (Concussion) |
| | SS | Removed From 10-Day IL (Torn tendon, left middle finger) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | SS | Called Up from Minors (Signed) |
| | CF | Removed From 10-Day IL (Sprained left wrist) |
| | P | Called Up from Minors (Signed) |
| | 3B | Called Up from Minors (Signed) |
| | C | Released (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | C | Placed on 7-Day IL (Concussion) |
| | C | Called Up from Minors (Signed) |
| | CF | Placed on 10-Day IL (Sprained left wrist) |
| | LF | Called Up from Minors (Signed) |
| | P | Reinstated from Bereavement/Family Medical Emergency List (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Released (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Placed on Bereavement/Family Medical Emergency List (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Outrighted to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Acquired Off Waivers (Signed) From |
| | P | NTR - Called Up From Minors (Signed) |
| | P | Released (Signed) |
| | P | Sent to Minors (Signed) |
| | CF | Sent to Minors (Signed) |
| | 3B | Removed From 10-Day IL (Strained left hamstring) |
| | P | NTR - Called Up From Minors (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Outrighted to Minors (Signed) |
| | LF | Sent to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | CF | Reinstated from Paternity Leave List (Signed) |
| | P | Transferred to 60-Day IL (Left lat strain) |
| | LF | Purchased From Minors (Signed) |
| | CF | Placed on Paternity Leave List (Signed) |
| | CF | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Reinstated from Bereavement/Family Medical Emergency List (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | C | Removed From 10-Day IL (Left knee strain) |
| | C | Recalled From Minors Rehab (Signed) |
| | C | Sent to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | SS | Recalled From Minors Rehab (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Placed on Bereavement/Family Medical Emergency List (Signed) |
| | 3B | Placed on 10-Day IL (Strained left hamstring) |
| | SS | Removed From 10-Day IL (Lower back strain) |
| | C | Sent to Minors for Rehabilitation (Signed) |
| | SS | Sent to Minors for Rehabilitation (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Transferred to 60-Day IL (Right elbow inflammation) |
| | C | Placed on 10-Day IL (Left knee strain) |
| | C | Purchased From Minors (Signed) |
| | SS | Sent to Minors (Signed) |
| | SS | Signed as Free Agent (one-year contract) |
| | P | Outrighted to Minors (Signed) |
| | P | NTR - Called Up From Minors (Signed) |
| | SS | Placed on 10-Day IL (Lower back strain) |
| | 2B | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Return of 27th man (Signed) |
| | SS | Placed on 10-Day IL (Torn tendon, left middle finger) |
| | SS | Reinstated From League Suspension (Signed) |
| | P | Called Up from Minors (recalled as 27th roster player) |
| | P | Released (Signed) |
| | SS | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | SS | Starting to Serve Suspension (Signed) |
| | P | Released (Signed) |
| | 3B | Released (Signed) |
| | P | Acquired Off Waivers (Signed) From |
| | P | Sent to Minors (Signed) |
| | 3B | Sent to Minors (Signed) |
| | CF | Removed From 10-Day IL (Lightheadedness, blurred vision) |
| | 3B | Removed From 10-Day IL (Bone bruise, right hand) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | 3B | Recalled From Minors Rehab (Signed) |
| | CF | Recalled From Minors Rehab (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Traded (for C Reese McGuire, three-player deal) From |
| | C | Traded (for LHP Jake Diekman, three-player deal) To |
| | SS | Suspension Announced By League (two games) |
| | P | Outrighted to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | NTR - Called Up From Minors (Signed) |
| | CF | Sent to Minors for Rehabilitation (Signed) |
| | 3B | Sent to Minors for Rehabilitation (Signed) |
| | P | Return of 27th man (Signed) |
| | P | Called Up from Minors (recalled as 27th roster player) |
| | CF | Placed on 10-Day IL (Lightheadedness, blurred vision) |
| | C | Removed From 10-Day IL (Lower back spasms) |
| | C | Recalled From Minors Rehab (Signed) |
| | P | Return of 27th man (Signed) |
| | P | Called Up from Minors (recalled as 27th roster player) |
| | C | Sent to Minors for Rehabilitation (Signed) |
| | LF | Recalled From Minors Rehab (Signed) |
| | 3B | Placed on 10-Day IL (Bone bruise, right hand) |
| | 2B | Transferred to 60-Day IL (Torn ACL, right knee) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | CF | Sent to Minors (Signed) |
| | CF | Removed From 10-Day IL (Strained right hamstring) |
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