San Jose Earthquakes (5-21-2, 15th in the Western Conference) vs. Seattle Sounders FC (13-9-7, fifth in the Western Conference)
Inter Miami CF (19-4-5, first in the Eastern Conference) vs. Atlanta United FC (8-13-7, 10th in the Eastern Conference)
Charlotte FC (10-10-8, seventh in the Eastern Conference) vs. Orlando City SC (11-10-7, fifth in the Eastern Conference)